Research & Diagnostics

Research & Diagnostics

The discipline has access to two laboratories: the laboratory for practical work with students and the Human Genomics Laboratory (LGU), part of the Diagnostic and Treatment Centre of the UMF in Craiova. In the last 8 years the LGU has become the genetic diagnostic laboratory of the Dolj Regional Centre for Medical Genetics. The diagnostic work of the LGU is carried out in three main modules with complementary activities: Molecular Genetics, Cytogenetics and Cell Cultures. The refurbishment of the laboratories, as well as the additional acquisition of high performance equipment was carried out through the TARGET project (Research and Treatment Centre in Gastroenterology by Imaging Methods and Molecular Techniques) - funded by ANCS with more than 10.000.000 euro. Equipping these modules with modern advanced genetic analysis systems enables comprehensive evaluations to be carried out in medical fields as diverse as Obstetrics-Gynaecology (prenatal diagnosis), Gastroenterology, Paediatric Neurology, etc. Among the genetic methods available in the LGU are: classical and molecular karyotyping (Comparative Genomic Hybridization), Real-Time PCR, Microarray, DNA fragment sequencing and analysis (e.g. MLPA), next generation sequencing (gene panel, whole exome sequencing, transcriptome).

The LGU is constantly developing both by equipping itself with specific high-tech equipment, introducing and optimising new methods of human genome assessment, and by training staff. This process is supported by the active participation of laboratory members in more than 30 national/international research/infrastructure development or training projects. Among the most important research projects carried out or ongoing at the LGU are:

REACT (Real-time Evaluation of Treatment Effects in Advanced ColorecTal Carcinoma) - Granturi Suport - Bridge Grant și TANDEM (Concurrent Tuberculosis and Diabetes Mellitus; unraveling the causal link, and improving care) – FP7 (The Seventh Framework Programme), RID-TB (Role of immunogenetic factors and vitamin D deficiency in tuberculosis), FUSE (Functional Genomics in severe infections) - POC-A1.1.4-E-2015 (SMIS 2014+P_37_745), PROGENERARE (Improving the PROFESSIONAL competences of medical staff involved in the performance of medical acts in specialties relevant to the multidisciplinary management of RARE GENETIC DISEASES).

 

Research and diagnostic activities are carried out in Human Genomics Laboratory.

Actualizat la 15.02.2024, 09:32