8 months
Dynamics Of GABAB Receptor Expression In Oligodendrocytes And Their Precursors During Development, Aging And Remyelination
- 1 EUR
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ObjectivesCreation of a web page dedicated to the project Defining behavioral testing and imaging protocols for two-photon microscopy
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ActivitiesQuantification of GABABR expression in oligodendrocyte cells and its precursors Assessing the role of GABAR in laboratory animal behavior Physiological characterization of the GABABR signaling cascade at the level of oligodendrocytes and its precursors
12 months
Determination Of Intracellular Signaling Pathways Triggered By GABAB Receptor Activation
- 1 EUR
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ObjectivesFinalization of the draft related to the way in which signaling is carried out with the help of the GABAB receptor. Beginning of drafting related to how the GABAB receptor is involved in demyelination and how it affects animal behavior. The obtained results will be the subject of an international scientific communication. Annual report.
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ActivitiesContinued A 2.2 Assessing the impact that the GABAB receptor has on the processes of remyelination and myelin formation Continuation A 1.2 Evaluation of the role of GABAR in laboratory animal behavior
12 months
Contribution Of Oligodendroglial GABAB Receptors To Social And Motor Behavior In Experimental Mice
- 1 EUR
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ObjectivesInitiation of drafting related to how GABAB receptor signaling is accomplished A specialized article published in an ISI indexed journal with an impact factor over 2. Annual scientific report.
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ActivitiesContinuation A 1.1 Quantification of GABABR expression in oligodendrocyte cells and its precursors Evaluation of the impact that the GABAB receptor has in the processes of remyelination and myelin formation Continuation A 1.2 Evaluation of the role of GABAR in laboratory animal behavior Continuation A 1.3 Physiological characterization of the GABABR signaling cascade at the level of oligodendrocytes and its precursors
3 months
Continued A 2.2 Assessing The Impact That The GABAB Receptor Has On The Processes Of Remyelination And Myelin Formation
- 1 EUR
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ObjectivesCompletion of the report related to how the GABAB receptor is involved in demyelination and how it affects animal behavior Creation of a final scientific report.
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Activities1.Continuation of A 2.2 Evaluation of the impact that the GABAB receptor has in the processes of remyelination and myelin formation 2.Continuation A 1.2 Evaluation of the role of GABAR in the behavior of the laboratory animal