Sistem de microinjecție printat 3D
3D printed microinjection syringe pump
A simple and cheap custom-made plastic 3D printed pump can be utilized to drive a variety of syringes, varying from classical ml range syringes, to very low volume Hamilton syringes. This simple equipment, if well controlled, can successfully replace in the lab most of the very expensive injectomates available for research use.
A metallic high-torque mini servo (our model is designed to encase this type of servo: https://www.pololu.com/product/997) can be very precisely controlled utilizing a cheap DC-DC Step Down Converter.
The schematic diagram showed below illustrates the main parts of this pump, and each individual part is freely available for download as a .stl file (designed utilising Autodesk Tinkercad). Our model has been printed using a Tiertime UpBoxPlus 3D printer, 1.75 mm-thick Tiertime PLA filament, at the highest density meshwork available from this printer (0.2 mm layer thickness).
Files list:
- Servo support (download ZIP file)
- Base (download ZIP file)
- Servo coupling (download ZIP file)
- Piston (download ZIP file)
- Micro syringe holder (download ZIP file)
Below is a view of our working model, utilized for slow injection of µl-order volumes (2 minutes for 1ml). The inset represents the speed and sense control unit. The needle of the Hamilton syringe is hydraulically connected with the injection glass pipette using Teflon inextensible tubing (0.5 mm inner diameter), and gun silicone oil.
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Proiecte de cercetare:
1. Nanostructuri bioactive pentru strategii terapeutice inovatoare PN-III-P1-1.2-PCCDI-2017-
0749. Proiect nr 45PCCDI din 16/04/2018; Durata proiect: 2018 – 2022 (coordonator Profesor
univ. dr. Mogoanta Laurentiu);
2. Mecanisme si biomarkeri de raspuns si rezistenta la terapiile curente tintite ale cancerului
gastric (THERRES). Autoritatea contractanta UEFISCDI - tip proiect PN-III-P4-ID-PCCF2016-
0158, Contract: PCCF 17/2018; Durata proiect: 19.10.2018 – 20.10.2022 (48 luni); Valoarea
totala a proiectului: 8.400.000 lei; Coordonator: Institutul Clinic Fundeni; Director de proiect:
Prof Dr Irinel Popescu; Institutii partenere in proiect: P1 – Universitatea de Medicina si
Farmacie din Craiova; (coordonator partener Profesor univ dr. Saftoiu Adrian);
3. Analiza structurala si modularea functionala a drenajului fluidului perivascular si al
amiloidului Abeta in creier, Autoritatea contractanta UEFISCDI – tip proiect PN-III-P2-2.1-
PED-2016, valoare: 600.000 RON, 01.2017 - 31.12.2018 (coordonator Profesor univ. dr. Pirici
Nicolae-Daniel);
4. BImodal treatment for ischemic STroke And high definition whole bRain microscopic imaging
(BISTAR), Contract 160/01.10.2015, Autoritatea contractanta UEFISCDI – tip proiect PN-II-RU-
TE-2014, valoare: 550.000 RON, 01.10.2015 - 30.09.2017 (coordonator Profesor univ. dr.
Pirici Nicolae-Daniel);
5. Participarea celulelor gliale in remodelarea vasculara consecutiva accidentului vascular
cerebral ischemic - Proiectul Sprijinirea cercetarii prin formarea de specialisti in cadrul
programului de studii postdoctorale, POSDRU/89/1.5/S/64109, Contract 7301/196 din
24.06.2010, Autoritatea contractanta UMF Carol Davila-Bucuresti, valoare: 123.000 RON,
01.06.2010-01.12.2012 (coordonator UMF Carol Davila);
6. Real-time Evaluation of Treatment Effects in Advanced ColorecTal Carcinoma- REACT.,
Contract 7/2012, Autoritatea contractanta UEFISCDI, valoare 1.494.940,00 RON, 05.07.2012 -
05.07.2014 (coordonator Profesor univ dr. Saftoiu Adrian);
7. Modelarea clinica si biomatematica a modificarilor vasculare consecutive chimioterapiei
si/sau terapiei anti-angiogene in carcinomul colorectal avansat, Contract CNCSIS-IDEI PN-II-
ID-PCE-2011-3-0664, Autoritatea contractanta UEFISCDI, valoare 1.699.584 RON, 05.10.2011
- 05.10.2014 (coordonator Profesor univ dr. Saftoiu Adrian);
8. Studiul corelativ pe model animal al modificarilor parenchimului cerebral aparute in
accidentele vasculare cerebrale, in functie de gravitatea factorului ischemic, Contract CNCSIS
ID-2188/2009, Autoritatea contractanta CNCSIS, valoare: 1.000.000 RON, 01.01.2009 -
31.12.2010 (coordonator Profesor univ. dr. Mogoanta Laurentiu);
9. Monitorizarea endoscopica, histologica, imunohistochimica si imunologica a leziunilor
premaligne gastrice si caracterizarea etapelor initiale ale invaziei oncogene în cancerul
gastric, Contract CEEX nr. 190/14.09.2006, Autoritatea contractanta MEdC-ANCS, valoare
1.460.000 RON, 2006-2008 (coordonator Profesor univ. dr. Mogoanta Laurentiu);
10. Biotehnologii inovative pentru obţinerea de alimente funcţionale din ciupercile genului
Pleurotus şi pregătiriea exploatării industriale. Proiect CEEX. 2005. Număr contract 21/
04.10.2005. Coordonator: Universitatea din Craiova. 2005 – 2007, 30.000 lei (coordonator
Profesor univ. dr. Mogoanta Laurentiu);
11. Optimizarea factorilor nutriţionali pentru obţinerea oului de consum îmbogăţit în acizi graşi
polinesaturaţi ω:3, aliment funcţional nou pentru piaţa românească. Proiect CEEX. 2005;
Numar grant 177/2005 Nr. contract de fiantare 1653/04.10.2005. Coordonator: IBNA
Baloteşti (coordonator Profesor univ. dr. Mogoanta Laurentiu);
12. Evaluarea factorului chimic de actiune al namolului sapropelic de Techirghiol in patologia
cronica degenerativa si inflamatorie a aparatului locomotor. Proiect VIASAN, cod: 043/ 2005-
2006. Coordonator proiect (Universitatea Ovidius Constanta), 150.000 lei (coordonator
Profesor univ. dr. Mogoanta Laurentiu);
13. Studiul modificărilor histologice şi imunohostochimice induse de osteoporoza senilă. Grant
cu Academia Română, cod 044/ 2005, 2005-2006, 50 000 lei (coordonator Profesor univ. dr.
Mogoanta Laurentiu);
14. Studiu histologic, biochimic şi imunologic privind modificările hepatice la copiii infectaţi cu
virusul imunodeficienţei umane (HIV) şi/sau decedaţi prin sindromul de imunodeficienţă
dobândită (SIDA). Cod ANSTI: 4130/2000., 2000 – 2001, 200 000 lei (coordonator Profesor
univ. dr. Mogoanta Laurentiu);
15. Studiu imunohistochimic, biochimic şi imunologic privind leziunile hepatice la copiii infectaţi
cu virusul imunodeficienţei umane (HIV). Cod MEC: 2837/ 2001- 2002 (coordonator Profesor
univ. dr. Mogoanta Laurentiu);
16. Neuropatologia infecţiei cu HIV. Contract de cercetare internaţional "PECO". Coordonator: -
Prof. Univ. Dr. Francoise Gray (Departement de Patolologie - Neuropatologie, HOSPITAL
Henri Mondor, 94010, CreteiL Cedex Franta; - UMF Craiova, 1993-1996, valoare: 100.000 $;
(coordonator HOSPITAL Henri Mondor, Franta).
Brevete de invenție:
1. Streba CT, Serbanescu MS, Pirici D, Gheonea IA, Streba L, Ungureanu BS, Rosu GC, Obleaga C.
Sistem pentru asistenţa rezecţiei hepatice laparoscopice bazat pe inteligenţă artificială şi
imagistică. Brevet de inventie nr. 135631 / 29.04.2022 eliberat de Oficiul de Stat pentru
Inventii si Marci.
2. Simionescu M, Titorencu ID, Rosca AM, Tutuianu R, Iacomi MD, Pruna V, Lascar I, Checherita
IA, Neagu TP, Mogoanta L, Mogosanu GD, Pirici D, Streba CT, Birca AC, Burdusel AC, Stoica
AE, Grumezescu AM, Chircov C. Hidrogeluri polimerice compozite cu proprietati
antibacteriene si cicatrizante si procedeu de obtinere a acestora. Brevet de inventie nr.
135361 / 30.12.2021 eliberat de Oficiul de Stat pentru Inventii si Marci.
3. Pirici I, Pirici D, Muresanu FD, Mogoanta L, Margaritescu C, Balseanu TA, Bogdan C. Dispozitiv
automat si procedeu de clarificare si imunomarcare in bloc a specimenelor anatomice si
anatomopatologice. Brevet de inventie nr. 131896 / 30.08.2018 eliberat de Oficiul de Stat
pentru Inventii si Marci.
4. Pirici ND, Margaritescu C, Simionescu C, Mogoanta L, Ion DA, Ciurea R, Stepan A. Procedeu
de includere in rasina acrilica a specimenelor anatomice si anatomopatologice. Brevet de
inventie nr. 129181 / 27.02.2015 eliberat de Oficiul de Stat pentru Inventii si Marci.
Lista publicatii principale:
1. Rosu GC, Mateescu VO, Simionescu A, Istrate-Ofiteru AM, Curcă GC, Pirici I, Mogoanta L,
Mindrila I, Kumar-Singh S, Hostiuc S, Pirici D. Subtle vascular and astrocytic changes in the
brain of coronavirus disease 2019 (COVID-19) patients. Eur J Neurol. 2022 Dec;29(12):3676-
3692 (IF=6.288)
2. Doeppner TR, Coman C, Burdusel D, Ancuta DL, Brockmeier U, Pirici DN, Yaoyun K, Hermann
DM, Popa-Wagner A. Long-term treatment with chloroquine increases lifespan in middle-
aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen
metabolism. Aging (Albany NY). 2022 May 23;14(10):4195-4210. Epub 2022 May 23
(IF=5.955)
3. Rotaru-Zavaleanu AD, Neacșu AI, Neacșu AD, Pirici D, Osiac E, Cătălin B, Gheonea DI. Effects
of Acute Sepsis on Cellular Dynamics and Amyloid Formation in a Mouse Model of
Alzheimer's Disease. Curr Issues Mol Biol. 2022; 44(9):3822-3834 (IF=2.695)
4. Sacerdoțianu VM, Ungureanu BS, Iordache S, Cazacu SM, Pirici D, Liliac IM, Burtea DE, Șurlin
V, Stroescu C, Gheonea DI, Săftoiu A. Gastric Cancer Angiogenesis Assessment by Dynamic
Contrast Harmonic Imaging Endoscopic Ultrasound (CHI-EUS) and Immunohistochemical
Analysis-A Feasibility Study. J Pers Med. 2022 Jun 21;12(7):1020 (IF=4.453).
5. Cherciu Harbiyeli IF, Constantin A, Cazacu IM, Burtea DE, Gheorghe EC, Popescu CF, Bejinariu
N, Georgescu CV, Pirici D, Ungureanu BS, Copăescu C, Săftoiu A. Technical Performance,
Overall Accuracy and Complications of EUS-Guided Interventional Procedures: A Dynamic
Landscape. Diagnostics (Basel). 2022 Jul 5;12(7):1641 (IF=3.992).
6. Istrate-Ofiteru AM, Berbecaru EIA, Zorila GL, Rosu GC, Dira LM, Comanescu CM, DRagusin RC,
Ruican D, Nagy RD, Iliescu DG, Mogoanta L, Pirici D. Specific Local Predictors That Reflect the
5
Tropism of Endometriosis-A Multiple Immunohistochemistry Technique. Int J Mol Sci, 2022,
17;23(10):5614 (IF=5.924)
7. Liliac IM, Ungureanu BS, Mărgăritescu C, Sacerdoțianu VM, Săftoiu A, Mogoantă L, Moraru E,
Pirici D. E-Cadherin Modulation and Inter-Cellular Trafficking in Tubular Gastric
Adenocarcinoma: A High-Resolution Microscopy Pilot Study. Biomedicines 2022, 10(2):349
(FI=4.757).
8. Osiac E, Mitran SI, Manea CN, Cojocaru A, Rosu GC, Osiac M, Pirici D, Bălșeanu AT, Cătălin B.
Optical coherence tomography microscopy in experimental traumatic brain injury. Microsc
Res Tech. 2021; 84(3):422-431 (FI = 2.117).
9. Ungureanu BS, Lungulescu CV, Pirici D, Turcu-Stiolica A, Gheonea DI, Sacerdotianu VM, Liliac
IM, Moraru E, Bende F, Saftoiu A. Clinicopathologic Relevance of Claudin 18.2 Expression in
Gastric Cancer: A Meta-Analysis. Front Oncol. 2021; 11:643872 (FI = 4.848).
10. Cîrstea AE, Buzulică RL, Pirici D, Ceauşu MC, Iman RV, Gheorghe OM, Neamţu SD, Stanca L,
Ene R, Kumar-Singh S, Mogoantă L. Histopathological findings in the advanced natural
evolution of the SARS-CoV-2 infection. Rom J Morphol Embryol. 2020;61(1):209-218 (FI =
1.411).
11. Popescu RC, Straticiuc M, Mustăciosu C, Temelie M, Trușcă R, Vasile BȘ, Boldeiu A, Mirea D,
Andrei RF, Cenușă C, Mogoantă L, Mogoșanu GD, Andronescu E, Radu M, Veldwijk MR, Savu
DI. Enhanced Internalization of Nanoparticles Following Ionizing Radiation Leads to Mitotic
Catastrophe in MG-63 Human Osteosarcoma Cells. Int J Mol Sci. 2020 Sep 30;21(19):E7220.
12. Ungureanu BS, Pirici D, Dima SO, Popescu I, Hundorfean G, Surlin V, Saftoiu A. Morphometric
Assessment of Confocal Laser Endomicroscopy for Pancreatic Ductal Adenocarcinoma, an Ex-
Vivo Pilot Study. Diagnostics (Basel). 2020; 10(11):923 (FI = 3.110).
13. Butucescu M, Crăiţoiu Ş, Mogoantă L, Rusu MC, Iacov-Crăiţoiu MM, Stoenescu MD. The oral
mucosa: Epithelial professional phagocytes, lymphatics, telocytes, and false telocytes. Ann
Anat. 2020 May;229:151462.
14. Docea AO, Calina D, Buga AM, Zlatian O, Paoliello MMB, Mogosanu GD, Streba CT, Popescu
WL, Stoica AE, Bîrcă AC, Vasile BS, Grumezescu AM, Mogoanta L. The Effect of Silver
Nanoparticles on Antioxidant/Pro-Oxidant Balance in a Murine Model. Int J Mol Sci, 2020,
21(4):1233. doi: 10.3390/ijms21041233, Impact Factor: 4.556
15. Slevin M, E Garcia-Lara E, Capitanescu B, Sanfeliu C, Zeinolabediny Y, AlBaradie R, Olah P,
Guo B, Pirici D, Napoli MD, Popa-Wagner A. Monomeric C-Reactive Protein Aggravates
Secondary Degeneration after Intracerebral Haemorrhagic Stroke and May Function as a
Sensor for Systemic Inflammation. J Clin Med. 2020; 9(9):E3053 (FI = 3.303).
16. Rosu GC, Catalin B, Balseanu TA, Laurentiu M, Claudiu M, Kumar-Singh S, Pirici D. Inhibition
of Aquaporin 4 Decreases Amyloid Aβ40 Drainage Around Cerebral Vessels. Mol Neurobiol.
2020; 57(11):4720-4734 (FI = 4.500).
17. Antohe M, Nedelcu RI, Nichita L, Popp CG, Cioplea M, Brinzea A, Hodorogea A, Calinescu A,
Balaban M, Ion DA, Diaconu C, Bleotu C, Pirici D, Zurac SA, Turcu G. Tumor infiltrating
lymphocytes: The regulator of melanoma evolution. Oncol Lett. 2019 May;17(5):4155-4161;
(FI = 1,871)
18. Toader OD, Rusu MC, Mogoantă L, Hostiuc S, Jianu AM, Ilie AC. An Immunohistochemical
Study of Gastric Mucosa and Critical Review Indicate that the Subepithelial Telocytes are
Prelymphatic Endothelial Cells. Medicina (Kaunas). 2019 Jun 27;55(7):316.
19. Balaure PC, Holban AM, Grumezescu AM, Mogoşanu GD, Bălşeanu TA, Stan MS, Dinischiotu
A, Volceanov A, Mogoantă L. In vitro and in vivo studies of novel fabricated bioactive
dressings based on collagen and zinc oxide 3D scaffolds. Int J Pharm. 2019 Feb 25;557:199-
207.
20. Burdușel AC, Gherasim O, Grumezescu AM, Mogoanta L, Ficai A, Andronescu E. Biomedical
Applications of Silver Nanoparticles: An Up-to-Date Overview. Nanomaterials (Basel), 2018,
31;8(9):681. doi: 10.3390/nano8090681, Impact Factor: 4.324
6
21. Burdușel AC, Gherasim O, Grumezescu AM, Mogoantă L, Ficai A, Andronescu E. Biomedical
Applications of Silver Nanoparticles: An Up-to-Date Overview. Nanomaterials (Basel). 2018
Aug 31;8(9):681.
22. Iancu CB, Rusu MC, Mogoantă L, Hostiuc S, Grigoriu M. Myocardial Telocyte-Like Cells: A
Review Including New Evidence. Cells Tissues Organs. 2018;206(1-2):16-25.
23. Ficai D, Grumezescu V, Fufă OM, Popescu RC, Holban AM, Ficai A, Grumezescu AM,
Mogoanta L, Mogosanu GD, Andronescu E. Antibiofilm Coatings Based on PLGA and
Nanostructured Cefepime-Functionalized Magnetite. Nanomaterials (Basel). 2018 Aug
21;8(9):633
24. Rusu MC, Mogoantă L, Pop F, Dobra MA. Molecular phenotypes of the human kidney: Myoid
stromal cells/telocytes and myoepithelial cells. Ann Anat. 2018 Jul;218:95-104.
25. Calinescu A, Turcu G, Nedelcu RI, Brinzea A, Hodorogea A, Antohe M, Diaconu C, Bleotu C,
Pirici D, Jilaveanu LB, Ion DA, Badarau IA. On the Dual Role of Carcinoembryonic Antigen-
Related Cell Adhesion Molecule 1 (CEACAM1) in Human Malignancies. J Immunol Res. 2018
Oct 14;2018:7169081; (FI = 3,298)
26. Catalin B, Rogoveanu OC, Pirici I, Balseanu TA, Stan A, Tudorica V, Balea M, Mindrila I, Albu
CV, Mohamed G, Pirici D, Muresanu DF. Cerebrolysin and aquaporin 4 inhibition improve
pathological and motor recovery after ischemic stroke. CNS Neurol Disord Drug Targets.
2018; 17(4):299-308 (FI=2,506)
27. Boddaert J, Bielen K, 's Jongers B, Manocha E, Yperzeele L, Cras P, Pirici D, Kumar-Singh S.CD8
signaling in microglia/macrophage M1 polarization in a rat model of cerebral ischemia. PLoS
One. 2018; 13(1):e0186937 (FI = 2,806)
28. Pirici I, Balsanu TA, Bogdan C, Margaritescu C, Divan T, Vitalie V, Mogoanta L, Pirici D, Carare
RO, Muresanu DF. Inhibition of Aquaporin-4 Improves the Outcome of Ischaemic Stroke and
Modulates Brain Paravascular Drainage Pathways. Int J Mol Sci. 2017; 23;19(1). pii: E46; (FI =
3,687)
29. Popescu RC, Andronescu E, Vasile BȘ, Truşcă R, Boldeiu A, Mogoantă L, Mogoșanu GD,
Temelie M, Radu M, Grumezescu AM, Savu D. Fabrication and Cytotoxicity of Gemcitabine-
Functionalized Magnetite Nanoparticles. Molecules. 2017 Jun 28;22(7):1080.
30. Cartana ET, Gheonea DI, Cherciu IF, Streaţa I, Uscatu CD, Nicoli ER, Ioana M, Pirici D,
Georgescu CV, Alexandru DO, Şurlin V, Gruionu G, Săftoiu A. Assessing tumor angiogenesis in
colorectal cancer by quantitative contrast-enhanced endoscopic ultrasound and molecular
and immunohistochemical analysis. Endosc Ultrasound. 2018; 7(3):175-183; (FI=2,728)
31. Held F, Morris AWJ, Pirici D, Niklass S, Sharp MMG, Garz C, Assmann A, Heinze HJ, Schreiber
F, Carare RO, Schreiber S. Vascular basement membrane alterations and β-amyloid
accumulations in an animal model of cerebral small vessel disease. Clin Sci (Lond). 2017;
131(10):1001-1013.
32. Rusu MC, Hostiuc S, Vrapciu AD, Mogoantă L, Mănoiu VS, Grigoriu F. Subsets of telocytes:
Myocardial telocytes. Ann Anat. 2017 Jan;209:37-44.
33. Ciurea RN, Rogoveanu I, Pirici D, Târtea GC, Streba CT, Florescu C, Catalin B, Puiu I, Târtea EA,
Vere CC. B2 adrenergic receptors and morphological changes of the enteric nervous system
in colorectal adenocarcinoma. World J Gastroenterol. 2017; 21;23(7):1250-1261; (FI=3,80)
34. Munteanu C, Pirici D, Stepan AE, Camen A, Margaritescu C. Maxillary calcifying epithelial
odontogenic tumor with sinus and buccal vestibule extension: a case report and
immunohistochemical study. Diagn Pathol. 2016 Nov 21;11(1):134; (FI=1.895)
35. Săndulescu O, Bleotu C, Matei L, Streinu-Cercel A, Oprea M, Drăgulescu EC, Chifiriuc MC,
Rafila A, Pirici D, Tălăpan D, Dorobăţ OM, Neguţ AC, Oţelea D, Berciu I, Ion DA, Codiţă I,
Calistru PI, Streinu-Cercel A. Comparative evaluation of aggressiveness traits in
staphylococcal strains from severe infections versus nasopharyngeal carriage. Microb
Pathog. 2016 Nov 14;102:45-53. doi: 10.1016/j.micpath.2016.11.006. (FI=1.888)
36. Rădulescu M, Holban AM, Mogoantă L, Bălşeanu TA, Mogoșanu GD, Savu D, Popescu RC, Fufă
O, Grumezescu AM, Bezirtzoglou E, Lazar V, Chifiriuc MC. Fabrication, Characterization, and
7
Evaluation of Bionanocomposites Based on Natural Polymers and Antibiotics for Wound
Healing Applications. Molecules. 2016 Jun 10;21(6):761.
37. Balaure PC, Popa RA, Grumezescu AM, Voicu G, Rădulescu M, Mogoantă L, Bălşeanu TA,
Mogoşanu GD, Chifiriuc MC, Bleotu C, Holban AM, Bolocan A. Biocompatible hybrid silica
nanobiocomposites for the efficient delivery of anti-staphylococcal drugs. Int J Pharm. 2016
Aug 30;510(2):532-42.
38. Oprea AE, Pandel LM, Dumitrescu AM, Andronescu E, Grumezescu V, Chifiriuc MC, Mogoantă
L, Bălşeanu TA, Mogoşanu GD, Socol G, Grumezescu AM, Iordache F, Maniu H, Chirea M,
Holban AM. Bioactive ZnO Coatings Deposited by MAPLE-An Appropriate Strategy to Produce
Efficient Anti-Biofilm Surfaces. Molecules. 2016 Feb 16;21(2):220.
39. Radulescu M, Andronescu E, Dolete G, Popescu RC, Fufă O, Chifiriuc MC, Mogoantă L,
Bălşeanu TA, Mogoşanu GD, Grumezescu AM, Holban AM. Silver Nanocoatings for Reducing
the Exogenous Microbial Colonization of Wound Dressings. Materials (Basel). 2016 May
6;9(5):345
40. Ungureanu BS, Pirici D, Margaritescu C, Gheonea IA, Trincu FN, Fifere A, Saftoiu A.
Endoscopic ultrasound guided injection of iron oxide magnetic nanoparticles for liver and
pancreas: a feasibility study in pigs. Med Ultrason. 2016; 18(2):157-62. doi:
10.11152/mu.2013.2066.182.eus. (FI=1,167)
41. Pirici D, Stanaszek L, Garz C, Niklass S, Heinze HJ, Kalinski T, Attems J, Schreiber S. Common
impact of chronic kidney disease and brain microhemorrhages on cerebral Aβ pathology in
SHRSP. Brain Pathol. 2017; 27(2):169-180 (FI=5,256)
42. Ilie CA, Rusu MC, Didilescu AC, Motoc AG, Mogoantă L. Embryonic hematopoietic stem cells
and interstitial Cajal cells in the hindgut of late stage human embryos: evidence and
hypotheses. Ann Anat. 2015 Jul;200:24-9. doi: 10.1016/j.aanat.2015.01.001. Epub 2015 Jan
31.
43. Grumezescu AM, Gestal MC, Holban AM, Grumezescu V, Vasile BS, Mogoantă L, Iordache F,
Bleotu C, Mogoșanu GD. Biocompatible Fe3O4 increases the efficacy of amoxicillin delivery
against Gram-positive and Gram-negative bacteria. Molecules, 2014, 19(4):5013-27. doi:
10.3390/molecules19045013, Impact Factor: 3.267
44. Grumezescu AM, Gestal MC, Holban AM, Grumezescu V, Vasile BS, Mogoantă L, Iordache F,
Bleotu C, Mogoşanu GD. Biocompatible Fe3O4 increases the efficacy of amoxicillin delivery
against Gram-positive and Gram-negative bacteria. Molecules. 2014 Apr 22;19(4):5013-27.
45. Holban AM, Grumezescu AM, Gestal MC, Mogoanta L, Mogosanu GD. Novel Drug Delivery
Magnetite Nano-systems Used in Antimicrobial Therapy. Current Organic Chemistry, 2014,
18(2): 185-191
46. Vanhommerig E, Moons P, Pirici D, Lammens C, Hernalsteens JP, De Greve H, Kumar-Singh S,
Goossens H, Malhotra-Kumar S. Comparison of biofilm formation between major clonal
lineages of methicillin resistant Staphylococcus aureus. PLoS One. 2014; Aug 8;9(8) (FI=3,234)
47. Gheonea DI, Streba CT, Vere CC, Şerbănescu M, Pirici D, Comănescu M, Streba LA, Ciurea ME,
Mogoantă S, Rogoveanu I. Diagnosis system for hepatocellular carcinoma based on fractal
dimension of morphometric elements integrated in an artificial neural network. Biomed Res
Int. 2014; 2014:239706. doi: 10.1155/2014/239706. Epub 2014 Jun 16 (FI=2,706)
48. Mărgaritescu C, Pirici D, Cherciu I, Bărbălan A, Cârtână T, Săftoiu A. CD133/CD166/Ki-67 triple
immunofluorescence assessment for putative cancer stem cells in colon carcinoma. J
Gastrointestin Liver Dis. 2014; Jun;23(2):161-70 (FI = 2,202)
49. Ciocâlteu A, Săftoiu A, Cârţână T, Gruionu LG, Pirici D, Georgescu CC, Georgescu CV, Gheonea
DI, Gruionu G. Evaluation of new morphometric parameters of neoangiogenesis in human
colorectal cancer using confocal laser endomicroscopy (CLE) and targeted panendothelial
markers. PLoS One. 2014; Mar 10;9(3) (FI=3,234)
50. Mogoanta L, Ciurea M, Pirici I, Margaritescu C, Simionescu C, Ion DA, Pirici D. Different
dynamics of aquaporin 4 and glutamate transporter 1 distribution in the perineuronal and
8
perivascular compartments during ischemic stroke. Brain Pathol. 2014; Sep; 24(5):475-93;
(FI=4,643)
51. Simionescu C, Mărgăritescu C, Stepan A, Pirici D, Ciurea R, Cernea N. Tumor angiogenesis,
macrophages and mast cell microdensities in endometrioid endometrial carcinoma. Oncol
Lett. 2013; Aug;6(2):415-420 (FI=0,987)
52. Cârţână T, Săftoiu A, Gruionu LG, Gheonea DI, Pirici D, Georgescu CV, Ciocâlteu A, Gruionu G
Confocal laser endomicroscopy for the morphometric evaluation of microvessels in human
colorectal cancer using targeted anti-CD31 antibodies. PLoS One. 2012; 7(12):e52815. doi:
10.1371/journal.pone.0052815. Epub 2012 Dec 28 (FI=3,73)
53. Di Napoli M, Godoy DA, Campi V, Masotti L, Smith CJ, Parry Jones AR, Hopkins SJ, Slevin M,
Papa F, Mogoanta L, Pirici D, Popa Wagner A. C-reactive protein in intracerebral hemorrhage:
time course, tissue localization, and prognosis. Neurology. 2012; Aug 14;79(7):690-9. doi:
10.1212/WNL.0b013e318264e3be. Epub 2012 Aug 1 (FI = 8,249)
54. Buckwalter JA, Wright T, Mogoanta L, Alman B. Plagiarism: an assault on the integrity of
scientific research. J Orthop Res. 2012 Dec;30(12):1867-8
55. Pirici D, Pirici I, Mogoanta L, Margaritescu O, Tudorica V, Margaritescu C, Ion DA, Simionescu
C, Coconu M. Matrix metalloproteinase-9 expression in the nuclear compartment of neurons
and glial cells in aging and stroke. Neuropathology. 2012; 32(5):492-504 (FI=1,909)
56. Pirici D., Van Cauwenberghe C., Van Broeckhoven C., Kumar-Singh S. Fractal analysis of
amyloid plaques in Alzheimer's disease patients and mouse models. Neurobiol Aging. 2011;
32(9):1579-87 (FI = 6,189)
57. Kambouchner M., Pirici D., Uhl JF., Mogoanta L., Valeyre D., Bernaudin JF. Lymphatic and
blood microvasculature organization in pulmonary sarcoid granulomas. Eur Respir J. 2010; Jul
22. 37(4):835-40 (FI = 5,922)
58. Popa-Wagner A., Pirici D., Petcu EB., Mogoanta L., Buga AM., Rosen CL., Leon R., Huber J.
Pathophysiology of the vascular wall and its relevance for cerebrovascular disorders in aged
rodents. Curr Neurovasc Res. 2010; 1;7(3):251-67 (FI= 3,047)
59. Margaritescu C., Raica M., Pirici D., Simionescu C., Mogoanta L., Stinga AC., Stinga AS., Ribatti
D. Podoplanin expression in tumor-free resection margins of oral squamous cell carcinomas:
an immunohistochemical and fractal analysis study. Histol Histopathol. 2010; 25(6):701-11 (FI
= 2,502)
60. Margaritescu C., Pirici D., Stinga A., Simionescu C., Raica M., Mogoanta L., Stepan A., Ribatti
D. VEGF expression and angiogenesis in oral squamous cell carcinoma: an
immunohistochemical and morphometric study. Clin Exp Med. 2010; 10(4):209-14 (FI =
1,600)
61. Pirici D., Mogoanta L., Kumar-Singh S., Pirici I., Margaritescu C., Simionescu C., Stanescu R.
Antibody elution method for multiple immunohistochemistry on primary antibodies raised in
the same species and of the same subtype. J Histochem Cytochem. 2009; 57(6):567-75
(FI=2,372)
62. van der Zee J., Pirici D., Van Langenhove T., Engelborghs S., Vandenberghe R., Hoffmann M.,
Pusswald G., Van den Broeck M., Peeters K., Mattheijssens M., Martin JJ., De Deyn PP., Cruts
M., Haubenberger D., Kumar-Singh S., Zimprich A., Van Broeckhoven C. Clinical heterogeneity
in 3 unrelated families linked to VCP p.Arg159His. Neurology, 2009; 73(8):626-32 (FI=8,172)
63. Van Broeck B., Vanhoutte G., Pirici D., Van Dam D., Wils H., Cuijt I., Vennekens K., Zabielski
M., Theuns J., De Deyn PP., Van Der Linden A., Van Broeckhoven C., Kumar-Singh S.
Intraneuronal amyloid beta and reduced brain volume in a novel APP T714I mouse model for
Alzheimer's disease. Neurobiology of Aging. 2008; 29(2):241-52 (FI = 5,959)
64. van der Zee J., Gijselinck I., Pirici D., Kumar-Singh S., Cruts M., Van Broeckhoven C.
Frontotemporal lobar degeneration with ubiquitin-positive inclusions: a molecular genetic
update. Neurodegener Dis. 2007; 4(2-3):227-35 (FI = 2,989)
65. Cruts M., Gijselinck I., van der ZJ., Engelborghs S., Wils H., Pirici D., Rademakers R.,
Vandenberghe R., Dermaut B., Martin JJ., van DC., Peeters K., Sciot R., Santens P., De PT.,9
Mattheijssens M., Van den BM., Cuijt I., Vennekens K., De Deyn PP., Kumar-Singh S., Van
Broeckhoven C. Null mutations in progranulin cause ubiquitin-positive frontotemporal
dementia linked to chromosome 17q21. Nature, 2006; 442, 920-924 (FI = 26,681)
66. Pirici D., Vandenberghe R., Rademakers R., Dermaut B., Cruts M., Vennekens K., Cuijt I.,
Lubke U., Ceuterick C., Martin JJ., Van Broeckhoven C., Kumar-Singh S. Characterization of
ubiquitinated intraneuronal inclusions in a novel Belgian frontotemporal lobar degeneration
family. J Neuropathol Exp Neurol. 2006; 65(3):289-301 (FI = 4,371)
67. Kumar-Singh S., Theuns J., Van Broeck B., Pirici D., Dermaut B., Vennekens K., Corsmit E.,
Cruts M., Wang R., Van Broeckhoven C. Mean age-of-onset of familial alzheimer disease
caused by presenilin mutations correlates with both increased Abeta42 and decreased
Abeta40. Human Mutation, 2006; 27(7): 686-95 (FI=6,473)
68. Kumar-Singh S., Pirici D., Serneels S., Ceuterick C., McGowan E., Duff K., Hardy J., Dickson D.,
Van Broeckhoven C. Dense-core plaques in Tg2576 and PSAPP mouse models of Alzheimer's
disease are centered on vessel walls. American Journal of Pathology 2005; 167(2): 527-43
(FI=5,796)