REACT

Etape

 

Phase I ( )

Obiective

State-of-the-art study and project implementation

Activitati

Creation of a structured database
Establishing the experimental protocols

Phase II ( )

Obiective

Endoscopic imaging of tumor microenvironment in CRC patients

Activitati

Protocol-based inclusion of advanced CRC patients including in vivo and ex vivo CLE examination
Collection of tissue samples

Phase III ( )

Obiective

Better characterization of tumor microenvironment focusing on CR-CSCs

Activitati

Software analysis (quantification) of CLE images
Pathological and immunohistochemical analysis of the collected tissue samples
Laser microdissection techniques
qRT-PCR analysis